Rarraba abubuwan anticoagulant da fibrinolytic daga Agkistrodon acutus venom da tasirin su akan tsarin coagulation.
Manufar: Don nazarin tasirin thrombin da aka tsarkake kamar enzyme da plasmin daga Agkistrodon acutus venom akan tsarin coagulation na jini.
Hanyoyi: Thrombin kamar enzyme da plasmin an ware su kuma an tsarkake su daga dafin Agkistrodon acutus ta DEAE Sepharose CL-6B da Sephadex G-75 chromatography, kuma an lura da tasirin su akan tsarin tsarin coagulation ta hanyar gwaje-gwajen vivo.Sakamako: Thrombin kamar enzyme da plasmin an ware su daga dafin Agkistrodon acutus, kuma danginsu na awoyi sun kasance 39300 da 26600, bi da bi, Dukansu thrombin kamar enzyme da plasmin daga Agkistrodon acutus venom na iya tsawaita tsawon lokacin coagulation na jini, kunna prothrombin partially. lokaci, lokacin thrombin da lokacin prothrombin, kuma yana rage abubuwan da ke cikin fibrinogen, amma tasirin thrombin kamar enzyme ya fi karfi, yayin da plasmin yana nuna tasirin anticoagulant kawai a mafi girma, kuma haɗuwa da su biyu ya fi amfani da su guda ɗaya.
Ƙarshe:
Thrombin kamar enzyme da plasmin daga Agkistrodon acutus venom suna da tasiri akan tsarin coagulation na jini a cikin dabbobi, kuma haɗuwa da su biyu yana da tasirin anticoagulant.
Lokacin aikawa: Mayu-10-2023