Manufa: Don nazarin tasirin thrombin-kamar da fibrinolytic enzymes ware da kuma tsarkakewa daga wannan Agkistrodon acutus venom akan tsarin coagulation na jini.Hanyoyi: An ware nau'in thrombin-kamar da fibrinolytic enzymes kuma an tsarkake su daga Agkistrodon acutus venom ta DEAE-Sepharose CL-6B da Sephadex G-75 chromatography, kuma an lura da tasirin duka akan tsarin tsarin haɗin jini ta hanyar gwaje-gwajen vivo.Sakamako: Wani bangare guda na thrombin-like da fibrinolytic enzymes an ware su kuma an tsarkake su daga dafin Agkistrodon acutus, Ma'aunin kwayoyin su na dangi shine 39300 da 26600, bi da bi.A cikin gwaje-gwajen vivo sun tabbatar da cewa duka thrombin-kamar da fibrinolytic enzymes daga Agkistrodon acutus venom na iya tsawaita duk lokacin coagulation na jini, kunna lokaci na prothrombin, lokacin thrombin da lokacin prothrombin, da rage abun ciki na fibrinogen, amma rawar thrombin. kamar enzymes ya fi karfi, yayin da fibrinolytic enzymes kawai yana nuna tasirin anticoagulant a manyan allurai, Ƙarshe: Thrombin-like enzyme da fibrinolytic enzyme daga Agkistrodon acutus venom suna da tasiri a kan tsarin coagulation na jini a cikin dabbobi, kuma haɗin gwiwar biyu yana da tasirin anticoagulant a fili.
Lokacin aikawa: Janairu-19-2023